β-Nicotinamide mononucleotide, 99% (1g)



β-Nicotinamide mononucleotide, ≥99% (HPLC)
CAS: 1094-61-7
Synonym: NMN, β-NMN, β-Nicotinamide ribose monophosphate, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate
Empirical Formula (Hill Notation): C11H15N2O8P
Molecular Weight 334.22
Beilstein/REAXYS Number 3570187
EC Number 214-136-5
MDL number MFCD00038748
PubChem Substance ID 24897645

β-Nicotinamide mononucleotide  (“NMN”, “NAMN”, and “β-NMN”) is a nucleotide derived from ribose and nicotinamide. Like nicotinamide riboside (NR), NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH). In mice, NMN enters cells via the small intestines within 10 minutes converting to NAD+ through the Slc12a8 NMN transporter. Because NADH is a cofactor for processes inside mitochondria, for sirtuins, and for PARP, NMN has been studied in animal models as a potential neuroprotective and anti-aging agent. Dietary supplement companies have aggressively marketed NMN products claiming those benefits. Doses of up to 500 mg was shown safe in human.

NMN is also used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.


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